United States securities and exchange commission logo March 14, 2022 Allan Shaw Chief Financial Officer Portage Biotech Inc. 6 Adelaide Street East, Suite 300 Toronto, Ontario, Canada M5C1H6 Re: Portage Biotech Inc. Form 20-F for the Fiscal Year ended March 31, 2021 Filed July 29, 2021 Filed March 4, 2022 File No. 001-40086 Dear Mr. Shaw: We have completed our review of your filings. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Energy & Transportation